A REVIEW ON POLOXAMER AND HYDROXY PROPYL METHYL CELLULOSE COMBINATION AS THERMORESPONSIVE POLYMERS IN NOVEL OPHTHALMIC IN SITU GEL FORMULATION AND THEIR CHARACTERIZATION

نویسندگان

چکیده

Poor bioavailability is one of the most significant problems in delivery ocular drug system. Ophthalmic ointments, solutions and suspensions are frequently used dosage forms to treat disease, their effectiveness as a compromised by several limitations that lead poor bioavailability. In situ gel promising strategy improve drugs. The purpose this review discuss formulation characterization gel. This written based on data or information obtained using search engines scientific journals, focused Poloxamer 407 Hydroxy Propyl Methyl Cellulose (HPMC) bases combination.
 Active ingredients disease such Ciprofloxacin, Fluconazole Ofloxacin can be formulated with combination polymer gelling agent HPMC viscosity enhancer produce good quality forms. alternate solution for ophthalmic

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ژورنال

عنوان ژورنال: International Journal of Applied Pharmaceutics

سال: 2021

ISSN: ['0975-7058']

DOI: https://doi.org/10.22159/ijap.2021v13i1.39697